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Implementing enhancement #51

alex-d13 and others added 3 commits October 17, 2025 10:54
…iles

- Replace lapply with vapply in simulate_bulk() for better performance
- Fix TPM normalization consistency issue where cell-type profiles didn't sum to bulk TPM
- Add comprehensive test suite with 49 passing tests for cell-type profiles feature
- Ensure mathematical consistency: bulk TPM = sum of cell-type TPM profiles
- Maintain backward compatibility and existing functionality
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2 participants