Added na.rm parameter for getMeth regions. #45
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aerval wants to merge 2 commits intohansenlab:develfrom
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Added na.rm parameter for getMeth regions. #45aerval wants to merge 2 commits intohansenlab:develfrom
aerval wants to merge 2 commits intohansenlab:develfrom
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added 2 commits
October 24, 2016 10:10
Current coverage is 16.68% (diff: 0.00%)@@ master #45 diff @@
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If a given region contains CpGs with with coverage 0, they are currently excluded from the averaging of the methylation values in that region. This can be highly biased if CpGs in the region have different methylation values and are compared to samples with higher coverage. Now you get NA as return if
na.rm = FALSEfor those regions, so you can easily exclude them from analysis. In theory I would think that this might even be the default parameter, though I understand that we should not force it here for compatibility reasons.Notes: