This was a small side-project done with web.py and Postgres a couple of years back. It used the older HTTP Authentication based twitter API, and would calculate your social worth in dollars ;).
Klout and similar companies had not been started yet when this was online.
It should be easy to setup the database with the SQL files provided, or you can use the script
./loaddb.sh
You should be easily able to setup uWSGI for web.py and get the same running
Feel free to mail me at dipankarsarkar@gmail.com in case you need more help!