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22 changes: 13 additions & 9 deletions README.md
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Expand Up @@ -45,7 +45,16 @@ This package provides an implementation of the inference pipeline of [ProTCR](ht

## Running ProTCR

1. Inference
1. Model Parameters

The [ProTCR](https://github.com/bigict/tcr_pmhc) model parameters are hosted on [Hugging Face](https://huggingface.co/bigict/tcr_pmhc).

```bash
huggingface-cli download --local-dir params bigict/tcr_pmhc

```

2. Inference

Once you have installed ProTCR, you can test your setup using e.g. the following input `csv` file named `tcr_pmhc_input.csv`

Expand All @@ -63,13 +72,8 @@ This package provides an implementation of the inference pipeline of [ProTCR](ht
predict.sh --help
```
for further help.

2. Train

Create the 5-fold dataset first
```bash
bash data/train_data_fold_5.sh
```
## Known Issues

Please [create an issue](https://github.com/bigict/tcr_pmhc/issues/new) if it is not already listed in the [issues tracker](https://github.com/bigict/tcr_pmhc/issues)

ProTCR was fine-tuned from [ProFOLD2](https://github.com/bigict/ProFOLD2) by Reinforcement Learning.
Please follow the instruction to train [ProFOLD2](https://github.com/bigict/ProFOLD2)
1 change: 1 addition & 0 deletions requirements.txt
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@@ -1,3 +1,4 @@
click
sqlitedict
hmmer
huggingface_hub