KnowYourTarget

Create an HTML Dashboard to know more about effects and drugs targeting a gene using NCI60 and DepMap data

Requirement

You need R version above 4.0.0 to run this application. Other dependencies are:

• rcellminerData (>= 2.13)
• rcellminer (>= 2.12)
• rmarkdown (>= 2.9)
• depmap (>= 1.4)
• ggplot2 (>= 3.3.5)
• tidyr (>=1.1.3)
• dplyr (>= 1.0.2)
• knitr (>= 1.33)
• i2dash (>= 0.2.3)
• foreach (>= 1.5.1)
• doParallel (>= 1.0)
• ExperimentHub (>= 1.38.2)
• plotly (>= 4.9.4)
• DT (>= 0.18)
• stringr( >= 1.4)
• AnnotationHub (>=2.22)

How to install the R package

From Github

• Install Dependencies
• install.packages(c("dplyr","knitr","ggplot2","tidyr","foreach","doParallel","plotly","DT","stringr","rmarkdown","i2dash"))
• install.packages("BiocManager")
• BiocManager::install(c("rcellminerData","rcellminer","depmap","ExperimentHub","AnnotationHub"))
• Now install the devtools package
• install.packages("devtools")
• library(devtools)
• Run command install_github("ashishjain1988/KnowYourTarget")

More about the package library(KnowYourTarget)

##Create a dashboard for a gene using NCI60 and DepMap data getGeneEffectsDashboard(gene="CHEK1",outputFilePath=".",outputFileName="CHEK1-KnowYourTarget.html")