diff --git a/CMakeLists.txt b/CMakeLists.txt
index 402632e9..b6bd46b5 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -56,9 +56,17 @@ pkg_check_modules(EXPAT REQUIRED expat)
 pkg_check_modules(SQLITE3 sqlite3)
 include_directories(${RPM_INCLUDE_DIRS})
 include_directories(${EXPAT_INCLUDE_DIRS})
+if(APPLE)
+    include_directories(${OPENSSL_INCLUDE_DIRS})
+    link_directories(${RPM_LIBRARY_DIRS})
+    link_directories(${EXPAT_LIBRARY_DIRS})
+endif()
 
 ### External dependency: libsolv
 find_package(LibSolv REQUIRED ext)
+if(APPLE)
+    include_directories(${LibSolv_INCLUDE_DIRS})
+endif()
 
 ### External dependency: libcurl
 find_package(CURL REQUIRED)
diff --git a/client/CMakeLists.txt b/client/CMakeLists.txt
index 521ca6ac..21c45c49 100644
--- a/client/CMakeLists.txt
+++ b/client/CMakeLists.txt
@@ -43,6 +43,12 @@ add_library(${LIB_TDNF} SHARED
     varsdir.c
 )
 
+if(APPLE)
+    # On macOS, explicitly find and link libsolvext
+    find_library(LIBSOLVEXT_LIBRARY NAMES solvext)
+    target_link_libraries(${LIB_TDNF} ${LIBSOLVEXT_LIBRARY})
+endif()
+
 target_link_libraries(${LIB_TDNF}
     ${LIB_TDNF_COMMON}
     ${LIB_TDNF_SOLV}
diff --git a/client/includes.h b/client/includes.h
index f1dcff4a..3f155eb6 100644
--- a/client/includes.h
+++ b/client/includes.h
@@ -27,7 +27,12 @@
 #include <sys/file.h>
 #include <time.h>
 #include <sys/utsname.h>
+#ifdef __APPLE__
+#include <sys/param.h>
+#include <sys/mount.h>
+#else
 #include <sys/vfs.h>
+#endif
 #include <sys/types.h>
 
 #include <dirent.h>
diff --git a/cmake/CFlags.cmake b/cmake/CFlags.cmake
index 3100a1d3..cc4a0c0c 100644
--- a/cmake/CFlags.cmake
+++ b/cmake/CFlags.cmake
@@ -10,6 +10,11 @@ set(WARN_CFLAGS
     -Wno-sign-compare
 )
 
+if(APPLE)
+    # Add macOS-specific warning suppressions for external headers
+    list(APPEND WARN_CFLAGS -Wno-unused-parameter)
+endif()
+
 set(OPTIMIZE_CFLAGS
     -O2
     -fno-strict-aliasing
@@ -67,20 +72,36 @@ set(RELEASE_CFLAGS
     -s
 )
 
-set(FEATURE_FLAGS
-    -D_XOPEN_SOURCE=500
-    -D_DEFAULT_SOURCE
-)
+if(APPLE)
+    set(FEATURE_FLAGS
+        -D_DARWIN_C_SOURCE
+    )
+else()
+    set(FEATURE_FLAGS
+        -D_XOPEN_SOURCE=500
+        -D_DEFAULT_SOURCE
+    )
+endif()
 
 ### Combine all flags
-set(TDNF_CFLAGS
-    ${WARN_CFLAGS}
-    ${OPTIMIZE_CFLAGS}
-    ${SECURITY_CFLAGS}
-    ${EXTRA_WARN_CFLAGS}
-    ${EXTRA_SECURITY_CFLAGS}
-    ${FEATURE_FLAGS}
-)
+if(APPLE)
+    # On macOS, skip GCC-specific flags that don't work with Clang
+    set(TDNF_CFLAGS
+        ${WARN_CFLAGS}
+        ${OPTIMIZE_CFLAGS}
+        ${SECURITY_CFLAGS}
+        ${FEATURE_FLAGS}
+    )
+else()
+    set(TDNF_CFLAGS
+        ${WARN_CFLAGS}
+        ${OPTIMIZE_CFLAGS}
+        ${SECURITY_CFLAGS}
+        ${EXTRA_WARN_CFLAGS}
+        ${EXTRA_SECURITY_CFLAGS}
+        ${FEATURE_FLAGS}
+    )
+endif()
 
 if(CMAKE_BUILD_TYPE STREQUAL "Debug")
     list(APPEND TDNF_CFLAGS ${DEBUG_CFLAGS})
diff --git a/cmake/FindGpgme.cmake b/cmake/FindGpgme.cmake
index 88162f03..2eb8db61 100644
--- a/cmake/FindGpgme.cmake
+++ b/cmake/FindGpgme.cmake
@@ -10,8 +10,13 @@ find_library(GPGME_LIBRARY NAMES gpgme)
 
 # handle the QUIETLY and REQUIRED arguments and set GPGME_FOUND to TRUE
 # if all listed variables are TRUE
-find_package_handle_standard_args(gpgme DEFAULT_MSG
-                                  GPGME_LIBRARY GPGME_INCLUDE_DIR)
+if(APPLE)
+    find_package_handle_standard_args(Gpgme DEFAULT_MSG
+                                      GPGME_LIBRARY GPGME_INCLUDE_DIR)
+else()
+    find_package_handle_standard_args(gpgme DEFAULT_MSG
+                                      GPGME_LIBRARY GPGME_INCLUDE_DIR)
+endif()
 
 mark_as_advanced(GPGME_INCLUDE_DIR GPGME_LIBRARY )
 
diff --git a/cmake/FindLibSolv.cmake b/cmake/FindLibSolv.cmake
index 81e22f3a..f1b538cf 100644
--- a/cmake/FindLibSolv.cmake
+++ b/cmake/FindLibSolv.cmake
@@ -73,7 +73,11 @@ FOREACH(COMPONENT ${LibSolv_FIND_COMPONENTS})
     FIND_LIBRARY(LIBSOLV_${_UPPERCOMPONENT}_LIBRARY NAMES solv${COMPONENT})
     SET(LibSolv_${COMPONENT}_FIND_REQUIRED ${LibSolv_FIND_REQUIRED})
     SET(LibSolv_${COMPONENT}_FIND_QUIETLY ${LibSolv_FIND_QUIETLY})
-    FIND_PACKAGE_HANDLE_STANDARD_ARGS(LibSolv_${COMPONENT} DEFAULT_MSG LIBSOLV_${_UPPERCOMPONENT}_LIBRARY)
+    IF(APPLE)
+        FIND_PACKAGE_HANDLE_STANDARD_ARGS(LibSolv DEFAULT_MSG LIBSOLV_${_UPPERCOMPONENT}_LIBRARY)
+    ELSE()
+        FIND_PACKAGE_HANDLE_STANDARD_ARGS(LibSolv_${COMPONENT} DEFAULT_MSG LIBSOLV_${_UPPERCOMPONENT}_LIBRARY)
+    ENDIF()
     MARK_AS_ADVANCED(
     LIBSOLV_${_UPPERCOMPONENT}_FOUND
     LIBSOLV_${_UPPERCOMPONENT}_LIBRARY
@@ -91,5 +95,6 @@ IF(Solv_USE_STATIC_LIBS)
 ENDIF()
 
 IF(LibSolv_FOUND AND NOT LibSolv_FIND_QUIETLY)
-    MESSAGE(STATUS "Found LibSolv: ${LibSolv_INCLUDE_DIRS} ${LibSolv_LIBRARIES}")
+    MESSAGE(STATUS "Found LibSolv: ${LibSolv_INCLUDE_DIRS}")
+    MESSAGE(STATUS "  Libraries: ${LibSolv_LIBRARIES}")
 ENDIF()
diff --git a/cmake/FindOpenSSL.cmake b/cmake/FindOpenSSL.cmake
index a6043bcd..42c4f135 100644
--- a/cmake/FindOpenSSL.cmake
+++ b/cmake/FindOpenSSL.cmake
@@ -4,10 +4,24 @@
 #  OPENSSL_LIBRARIES - The libraries needed to use openssl-devel
 
 find_path(OPENSSL_INCLUDE_DIR openssl/sha.h)
-find_library(OPENSSL_LIBRARY NAMES libssl.so)
+if(APPLE)
+    # This *should* also work on Linux, but needs to be tested.
+    # Keeping this guarded for now.
+    find_library(OPENSSL_SSL_LIBRARY NAMES ssl)
+    find_library(OPENSSL_CRYPTO_LIBRARY NAMES crypto)
+    find_package_handle_standard_args(OpenSSL DEFAULT_MSG
+                                      OPENSSL_SSL_LIBRARY OPENSSL_CRYPTO_LIBRARY OPENSSL_INCLUDE_DIR)
+    set(OPENSSL_LIBRARY ${OPENSSL_SSL_LIBRARY})
 
-find_package_handle_standard_args(libssl DEFAULT_MSG
-                                  OPENSSL_LIBRARY OPENSSL_INCLUDE_DIR)
+else()
+    find_library(OPENSSL_LIBRARY NAMES libssl.so)
+    find_package_handle_standard_args(libssl DEFAULT_MSG
+                                      OPENSSL_LIBRARY OPENSSL_INCLUDE_DIR)
+endif()
 
-set(OPENSSL_LIBRARIES ${OPENSSL_LIBRARY})
+if(APPLE)
+    set(OPENSSL_LIBRARIES ${OPENSSL_SSL_LIBRARY} ${OPENSSL_CRYPTO_LIBRARY})
+else()
+    set(OPENSSL_LIBRARIES ${OPENSSL_LIBRARY})
+endif()
 set(OPENSSL_INCLUDE_DIRS ${OPENSSL_INCLUDE_DIR})
diff --git a/common/defines.h b/common/defines.h
index 90029450..fde745d4 100644
--- a/common/defines.h
+++ b/common/defines.h
@@ -27,3 +27,10 @@
  * in fedora docker images and as a result ci fails
  */
 #define TDNF_INSTANCE_LOCK_FILE     "/var/run/.tdnf-instance-lockfile"
+
+/* macOS compatibility: EBADFD doesn't exist on macOS */
+#ifdef __APPLE__
+#ifndef EBADFD
+#define EBADFD EIO
+#endif
+#endif
diff --git a/history/CMakeLists.txt b/history/CMakeLists.txt
index 133bb06f..51b0f0a3 100644
--- a/history/CMakeLists.txt
+++ b/history/CMakeLists.txt
@@ -26,8 +26,6 @@ set_target_properties(${LIB_TDNF_HISTORY} PROPERTIES POSITION_INDEPENDENT_CODE O
 install(TARGETS ${TDNF_HISTORY_UTIL_BIN} RUNTIME DESTINATION ${CMAKE_INSTALL_LIBEXECDIR}/tdnf COMPONENT binary)
 
 target_link_libraries(${TDNF_HISTORY_UTIL_BIN}
-    ${RPM_LIBRARIES}
-    ${SQLITE3_LIBRARIES}
     ${LIB_TDNF_HISTORY}
 )
 
diff --git a/tools/cli/lib/CMakeLists.txt b/tools/cli/lib/CMakeLists.txt
index 7f5e3ab4..08603237 100644
--- a/tools/cli/lib/CMakeLists.txt
+++ b/tools/cli/lib/CMakeLists.txt
@@ -31,8 +31,15 @@ add_library(${LIB_TDNF_CLI} SHARED
 
 target_link_libraries(${LIB_TDNF_CLI}
     ${LIB_TDNF_JSONDUMP}
+    ${LIB_TDNF}
 )
 
+if(APPLE)
+    target_link_libraries(${LIB_TDNF_CLI}
+        ${OPENSSL_LIBRARIES}
+    )
+endif()
+
 set_target_properties(${LIB_TDNF_CLI} PROPERTIES
     VERSION ${PROJECT_VERSION}
     SOVERSION ${PROJECT_VERSION_MAJOR}