diff --git a/inst/examples/DT-crosstalk/plotly-persist.R b/inst/examples/DT-crosstalk/plotly-persist.R
new file mode 100644
index 00000000..a74e23e1
--- /dev/null
+++ b/inst/examples/DT-crosstalk/plotly-persist.R
@@ -0,0 +1,15 @@
+library(plotly)
+library(crosstalk)
+library(DT)
+
+m <- SharedData$new(mtcars)
+bscols(
+  plot_ly(m, x = ~wt, y = ~mpg) %>%
+    add_markers() %>%
+    config(displayModeBar = FALSE) %>%
+    layout(
+      title = "Hold shift while clicking \n markers for persistent selection",
+      margin = list(t = 60)
+    ),
+  datatable(m)
+)
diff --git a/inst/htmlwidgets/datatables.js b/inst/htmlwidgets/datatables.js
index 1d451db6..b8bdedb5 100644
--- a/inst/htmlwidgets/datatables.js
+++ b/inst/htmlwidgets/datatables.js
@@ -320,7 +320,12 @@ HTMLWidgets.widget({
         }
 
         if (e.sender !== instance.ctselectHandle && e.value && e.value.length) {
-          $table[0].ctselect = keysToMatches(e.value);
+          var ctOpts = crosstalk.var("plotlyCrosstalkOpts").get() || {};
+          if (ctOpts.persistent === true) {
+            $table[0].ctselect = [].concat($table[0].ctselect, keysToMatches(e.value));
+          } else {
+            $table[0].ctselect = keysToMatches(e.value);
+          }
           table.draw();
         } else {
           if ($table[0].ctselect) {