diff --git a/Cargo.toml b/Cargo.toml
index a0bb22f..cc9eabb 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -16,7 +16,7 @@ default-run = "coverm"
 [dependencies]
 
 bio = "0.38.0"
-rust-htslib = { version="0.38.*", default-features = false }
+rust-htslib = { version="0.40.*", default-features = false }
 clap = "2.*"
 glob = "0.3.*"
 log = "0.4.*"