Questions about Gauge labels

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I'm a newbie with Prometheus_client.
I would like to ask if it is possible to customize the label.
The example is as follows
metrics_one = prometheus_client.Gauge("mysql_data", "mysql_data", ["label1", "label2", "label3", "label4", "label5", "label6"])
metrics_two = prometheus_client.Gauge("mysql_data", "mysql_data", ["label1", "label2", ])
metrics_three = prometheus_client.Gauge("mysql_data", "mysql_data", ["label1", "label3", ])
metrics_four = prometheus_client.Gauge("mysql_data", "mysql_data", ["label1", "label2", "label4" ])

But I have a lot of labels, I only need to use a few of them when I insert data，
Do I have to write all the metrics like this? Is there another way to do it?
And in the end, I finally hope to use flask to respond to the latest data of all labels of metrics.
@app.route('/metrics')
def metrics():
set_data_to_prometheus()
return Response(prometheus_client.generate_latest(metrics), mimetype="text/plain")

If so, I can only pass out the data of one metric.
Looking forward for your reply, thank you