Detailed results

[aleest21]

Hello and thank you for your work, I find it very interesting! I would like to know if it's possible to provide more details about the output of the test_ctdna() function, specifically specifying the details of the mutations detected as positive. Thank you! Alexis

[alkodsi]

Hi Alexis,
The test_ctDNA function will look at the mutations collectively and see if the support is exceeding what can be expected by chance. It doesn't call positive or negative individual mutations. If you are interested in quantifying the ref and alt reads supporting your individual mutations, you can use this function: https://alkodsi.github.io/ctDNAtools/reference/get_mutations_read_counts.html