diff --git a/neuroml/nml/nml.py b/neuroml/nml/nml.py
index f975c86..8d8c5b7 100644
--- a/neuroml/nml/nml.py
+++ b/neuroml/nml/nml.py
@@ -37,6 +37,7 @@
 import re as re_
 import typing
 from functools import cached_property, lru_cache
+from itertools import zip_longest
 from math import pi, sqrt
 from operator import attrgetter
 
@@ -44,7 +45,6 @@
 import networkx as nx
 import numpy
 from lxml import etree as etree_
-from six.moves import zip_longest
 
 import neuroml
 import neuroml.neuro_lex_ids
diff --git a/neuroml/nml/regenerate-nml.sh b/neuroml/nml/regenerate-nml.sh
index 64d587b..bfce5c5 100755
--- a/neuroml/nml/regenerate-nml.sh
+++ b/neuroml/nml/regenerate-nml.sh
@@ -23,6 +23,8 @@ regenerate () {
 
 
         PYTHONPATH="$PYTHONPATH:." generateDS -o nml.py --use-getter-setter=none --user-methods=helper_methods.py --export="write validate" --custom-imports-template=gds_imports-template.py $SCHEMA_FILE
+        # replace six
+        sed -i 's/from six.moves/from itertools/' nml.py
         # correct path to generatedssupersuper module file
         sed -i 's/from generatedssupersuper/from .generatedssupersuper/' nml.py
         sed -i 's/from generatedscollector/from .generatedscollector/' nml.py
diff --git a/setup.cfg b/setup.cfg
index 4162a76..8f6e785 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -26,11 +26,13 @@ classifiers =
 [options]
 install_requires =
     lxml
-    six
     networkx
-    numpy
-    tables
-    typing; python_version<"3.5"
+    # tables 3.10+ support numpy2x, but no wheels are provided for py<3.10
+    numpy<2.0; python_version<"3.10"
+    tables; python_version<"3.10"
+    # for py>3.10, specify minimum tables version and let that choose appropriate numpy
+    numpy; python_version>="3.10"
+    tables>3.10; python_version>="3.10"
     natsort
 
 packages = find: