Final proportion of non-zero values is large.

[ayeTown]

I start with a matrix which has 10.81% nonzero values. After using this imputation method this proportion changes to 55.95%. Is this reasonable compared to your experiments?

[Rohit-Satyam]

Hi @ayeTown. I also observe this. When using all samples together via merging their count matrices and then performing imputation, I observe increment of non-zero values from 0.5% to 17% only. However, if I separately impute them they go as high as 50%. Did you get any method to gauge if ALRA is performing over-imputation or not?

[yamihn]

I faced the same. Any solution?