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First thanks for such a nice tool.
From samblaster's stderr:
samblaster: Marked 260861786 of 1716036289 (15.201%) total read ids as duplicates using 26070192k memory in 1H6M37S(3996.760S) CPU seconds and 2H28S(7228S) wall time.
Any clue why could wall time be 2X cpu time? I'm writing read by read to stdin from python, perhaps I should buffer and write big chunks at the same time? By the way, I'm 100% sure IO is not the issue
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