diff --git a/projects/packages/sync/changelog/pr-47303 b/projects/packages/sync/changelog/pr-47303
new file mode 100644
index 000000000000..bbf768b4aff0
--- /dev/null
+++ b/projects/packages/sync/changelog/pr-47303
@@ -0,0 +1,4 @@
+Significance: minor
+Type: added
+
+REST_Endpoints: Add clear-queue endpoint to allow clearing a Sync queue via REST API.
diff --git a/projects/packages/sync/src/class-rest-endpoints.php b/projects/packages/sync/src/class-rest-endpoints.php
index 1bc84b08240b..10ca265f9e87 100644
--- a/projects/packages/sync/src/class-rest-endpoints.php
+++ b/projects/packages/sync/src/class-rest-endpoints.php
@@ -332,6 +332,17 @@ public static function initialize_rest_api() {
 				'permission_callback' => __CLASS__ . '::verify_default_permissions',
 			)
 		);
+
+		// Clear Sync queue.
+		register_rest_route(
+			'jetpack/v4',
+			'/sync/clear-queue',
+			array(
+				'methods'             => WP_REST_Server::EDITABLE,
+				'callback'            => __CLASS__ . '::clear_queue',
+				'permission_callback' => __CLASS__ . '::verify_default_permissions',
+			)
+		);
 	}
 
 	/**
@@ -810,6 +821,27 @@ public static function reset_locks() {
 		);
 	}
 
+	/**
+	 * Clear the Sync queue.
+	 *
+	 * @since $$next-version$$
+	 *
+	 * @return \WP_REST_Response
+	 */
+	public static function clear_queue() {
+		$queue = new Queue( 'sync' );
+		$queue->reset();
+
+		// Re-enable sending in case it was temporarily disabled during a pull.
+		delete_transient( Sender::TEMP_SYNC_DISABLE_TRANSIENT_NAME );
+
+		return rest_ensure_response(
+			array(
+				'success' => true,
+			)
+		);
+	}
+
 	/**
 	 * Verify that request has default permissions to perform sync actions.
 	 *
diff --git a/projects/packages/sync/tests/php/REST_Endpoints_Test.php b/projects/packages/sync/tests/php/REST_Endpoints_Test.php
index 0624087224c1..079f82b594fb 100644
--- a/projects/packages/sync/tests/php/REST_Endpoints_Test.php
+++ b/projects/packages/sync/tests/php/REST_Endpoints_Test.php
@@ -262,6 +262,27 @@ public function test_sync_reset_locks() {
 		$this->assertEquals( 200, $response->get_status() );
 	}
 
+	/**
+	 * Testing the `POST /jetpack/v4/sync/clear-queue` endpoint clears the sync queue.
+	 */
+	public function test_sync_clear_queue() {
+		$user = wp_get_current_user();
+		$user->add_cap( 'manage_options' );
+
+		set_transient( Sender::TEMP_SYNC_DISABLE_TRANSIENT_NAME, time() );
+
+		$request = new WP_REST_Request( 'POST', '/jetpack/v4/sync/clear-queue' );
+		$request->set_header( 'Content-Type', 'application/json' );
+		$response = $this->server->dispatch( $request );
+		$data     = $response->get_data();
+
+		$user->remove_cap( 'manage_options' );
+
+		$this->assertEquals( 200, $response->get_status() );
+		$this->assertTrue( $data['success'] );
+		$this->assertFalse( get_transient( Sender::TEMP_SYNC_DISABLE_TRANSIENT_NAME ) );
+	}
+
 	/**
 	 * Array of Sync Endpoints and method.
 	 *
@@ -283,6 +304,7 @@ public static function endpoint_provider() {
 			array( 'sync/data-check', 'GET', null ),
 			array( 'sync/data-histogram', 'POST', null ),
 			array( 'sync/locks', 'DELETE', null ),
+			array( 'sync/clear-queue', 'POST', null ),
 		);
 	}
 
diff --git a/projects/plugins/jetpack/changelog/pr-47303 b/projects/plugins/jetpack/changelog/pr-47303
new file mode 100644
index 000000000000..ebfae8c170f2
--- /dev/null
+++ b/projects/plugins/jetpack/changelog/pr-47303
@@ -0,0 +1,4 @@
+Significance: minor
+Type: enhancement
+
+Sync: Add clear-queue REST endpoint to allow clearing a Sync queue.